(Black Press Media file photo)

Vaccine against fentanyl shows promising results in rats: U.S. study

Rats chose food more times instead of fentanyl after receiving the vaccine treatment

A vaccine against fentanyl addiction is showing promising results in a recent study.

Research published in the American journal Neuropsychopharmacology last week found that a fentanyl antigen (an antigen triggers the production of antibodies) combined with a type of tetanus vaccine decreased drug-taking behaviour in rats and increased food choices, according to a news release.

British Columbia reported more than 1,300 illicit drug overdose deaths related to fentanyl in 2018, an increase of seven per cent from 2017.

“More effective and readily available treatments for opioid use disorder are needed to tackle the current crisis,” said lead authors Kim Janda, a professor at Scripps Research in San Diego, and Dr. Matthew Banks of the Virginia Commonwealth University School of Medicine.

READ MORE: Health Canada tightens marketing requirements for opioid prescriptions

“One strategy includes using opioid-targeted vaccines to elicit antibody production by the host’s immune system that recognize and block the passage of a specific opioid into the brain and peripheral organs/tissue.”

The study focused on the rats’ behavioural patterns and the number of times they chose fentanyl injections or food.

Before the treatment, rats chose a large amount of fentanyl, but within four weeks of being vaccinated, the number of times they chose the drug decreased.

The effectiveness of the vaccine has not been studied in humans.



joti.grewal@bpdigital.ca

Like us on Facebook and follow us on Twitter

Just Posted

Four vehicle accident causing southbound gridlock on Highway 11

Accident occurred around 12:30 p.m. at intersection with Valley Road, ambulance on scene

VIDEO: Canada’s only mobile shower trailer for homeless run by Abbotsford Mennonites

Refresh Mobile Showers started operations on May 1, provided over 550 showers

Mission Festival of Trees wraps up Saturday

Event concludes with reading of A Child’s Christmas in Wales at All Saints Anglican Church

Planning price tag revealed for futuristic ‘We Town’ concept in Abbotsford

Developer says highrises would house 30,000, but Abbotsford mayor says project is in wrong place

Petition for free menstrual products turned over to UFV president

Almost 1,300 signatures collected calling for all campus bathrooms to be stocked

VIDEO: Success of wildlife corridors in Banff National Park has advocates wanting more

Demand for more highway protection escalated after seven elk were killed by a semi-trailer near Canmore

VIDEO: Fire destroys Big White Ski Resort chalet

Social media eulogies peg the property, nicknamed “The Pharamacy,” as both loved and hated

Prince George RCMP use bait packages to catch porch pirates over the holidays

First-in-Canada program with Amazon looks to combat parcel theft

Surrey councillor wants the policing transition process to ‘immediately stop’

Brenda Locke to make motion at Dec. 16 meeting to reconsider current plan

Man pleads guilty to second-degree murder in 2017 Stanley Park stabbing

Lubomir Kunik was found by a man out walking his dog on the beach late on Feb. 1, 2017

Vancouver homeless camp brings community, safety, home, says resident

Encampment in the city’s Downtown Eastside is one of many that have sprung up in B.C.

Nanaimo mechanical engineer creates thief tracking program

Nanaimo Thief Tracking lets users plot and share information about thefts online

Mayor wants B.C. to institutionalize severely mental ill people who are homeless

Those suffering from mental health conditions, such as schizophrenia, need specialized care, mayor says

Most Read