(Black Press Media file photo)

Vaccine against fentanyl shows promising results in rats: U.S. study

Rats chose food more times instead of fentanyl after receiving the vaccine treatment

A vaccine against fentanyl addiction is showing promising results in a recent study.

Research published in the American journal Neuropsychopharmacology last week found that a fentanyl antigen (an antigen triggers the production of antibodies) combined with a type of tetanus vaccine decreased drug-taking behaviour in rats and increased food choices, according to a news release.

British Columbia reported more than 1,300 illicit drug overdose deaths related to fentanyl in 2018, an increase of seven per cent from 2017.

“More effective and readily available treatments for opioid use disorder are needed to tackle the current crisis,” said lead authors Kim Janda, a professor at Scripps Research in San Diego, and Dr. Matthew Banks of the Virginia Commonwealth University School of Medicine.

READ MORE: Health Canada tightens marketing requirements for opioid prescriptions

“One strategy includes using opioid-targeted vaccines to elicit antibody production by the host’s immune system that recognize and block the passage of a specific opioid into the brain and peripheral organs/tissue.”

The study focused on the rats’ behavioural patterns and the number of times they chose fentanyl injections or food.

Before the treatment, rats chose a large amount of fentanyl, but within four weeks of being vaccinated, the number of times they chose the drug decreased.

The effectiveness of the vaccine has not been studied in humans.



joti.grewal@bpdigital.ca

Like us on Facebook and follow us on Twitter

Just Posted

Abbotsford Regional Hospital’s ER expansion still in the works

Deadline for construction proposals recently closes, but construction timeline unknown

Money in to finish Lougheed Highway twinning

$29 million to complete four laning of four-kilometre stretch in Maple Ridge, but no start date

Figures reveal spike in highway traffic jams between Abbotsford and Langley

Nearly one in 20 westbound vehicles between Abbotsford and Langley clocked at under 60 km/h

Mission council grants third reading to Tunbridge townhome proposal

Speakers at public hearing voice concerns, say project will ‘stick out like an eyesore’

Rolling with the punches

Abbotsford Mission Boxing Club settles into new home on Maclure Road

Rich the Vegan scoots across Canada for the animals

Rich Adams is riding his push scooter across Canada to bring awareness to the dog meat trade in Asia

A year later, ceremony commemorates victims of the Danforth shooting

It’s the one-year anniversary of when a man opened fire along the bustling street before shooting and killing himself

Japanese Canadians call on B.C. to go beyond mere apology for historic racism

The federal government apologized in 1988 for its racism against ‘enemy aliens’

B.C. VIEWS: NDP pushes ahead with Crown forest redistribution

This isn’t the time for a radical Indigenous rights agenda

Two dead in two-vehicle crash between Revelstoke and Golden

RCMP are investigating the cause of the crash

Ottawa fights planned class action against RCMP for bullying, intimidation

The current case is more general, applying to employees, including men, who worked for the RCMP

Alberta judge denies B.C.’s bid to block ‘Turn Off the Taps’ bill

He said the proper venue for the disagreement is Federal Court

Canadian high school science courses behind on climate change, says UBC study

Researchers found performance on key areas varies by province and territory

Most Read